2017
- CHAIR-ADMIN (website)
- COLOR VISION IN INHERITED RETINAL DEGENERATIONS (website)
- COORDINATING-CENTER (website)
- ENROLLMENT-CENTER (website)
- GENETIC; CELLULAR AND MOLECULAR MECHANISMS IN AUTOIMMUNITY TO RETINA (website)
- MOLECULAR GENETICS OF EARLY EYE DEVELOPMENT (website)
- PRE-CLINICAL AND CLINICAL STUDIES OF NTBC AND OTHER COMPOUNDS AS POTENTIAL TREATMENTS FOR ALBINISM (website)
- RESOURCE-CENTER (website)
2016
- GENERATION OF INDUCED PLURIPOTENT STEM (IPS) CELL LINES FROM SOMATIC CELLS OF PARTICIPANTS WITH EYE DISEASES AND FROM SOMATIC CELLS OF MATCHED CONTROLS (website)
- NATURAL HISTORY OF SPINOCEREBELLAR ATAXIA TYPE 7 (SCA7) (website)
- THE FOCAL ELECTRO-OCULOGRAM IN MACULAR DISEASE (website)
- THERAPEUTICS FOR THE CHORIORETINA (website)
2015
- Biocompatible retinal prosthesis based on a conjugated polymer photoactive layer
- Biomechanical analysis of the cornea and keratoconus
- Cone opsin in photoreceptor degeneration
- Cytomegalovirus retinitis pathogenesis: mechanisms of retinal tissue destruction
- Disease mechanisms in best disease
- Disease models for high throughput screens
- Drug discovery and mechanistic study of p23h rhodopsin associated retinitis pigmentosa
- EVALUATION OF INTERFERON GAMMA-1B ADMINISTERED TOPICALLY FOR MACULAR EDEMA/INTRARETINAL SCHISIS CYSTS IN ROD-CONE DYSTROPHY (RCD) & ENHANCED S-CONE SYNDROME (ESCS) (website)
- Gene silencing and gene editing in phototransduction
- GENETIC VARIANTS; EPIGENOME AND RETINAL DISEASE PHENOTYPES (website)
- Human connectomes for low vision, blindness, and sight restoration
- Ire1 alpha inhibitors for retinal degenerative diseases
- Manufacturing pathogen inactivated platelet lysate to treat corneal inflammation
- MOLECULAR GENTICS AND BIOSTATISTICS (website)
- Molecular therapies for lebers congenital amaurosis caused by kcnj13 mutations
- Mouse model for eyelid disease: congenital blepharophimosis
- OCULAR GENE THERAPY (website)
- PRECLINICAL SAFETY STUDIES (website)
- Regulation of eye morphogenesis
- Retinitis pigmentosa therapy with human embryonic stem cell- and induced pluripotent stem cell-derived photoreceptor progenitors
- Secondary analysis of the data from the telemedicine approaches to evaluating acute-phase rop (e-rop)
- The molecular basis of liver induced retinal blood vessel plasticity
- The role of complement in recessive stargardt disease
- The role of plasmacytoid dendritic cells in corneal immunity
- The role of transcription factor 4 repeat expansion in fuchs endothelial corneal dystrophy
- Wavefront guided customized soft contact lens for highly aberrated eyes
2014
- A high content screening approach for the retinal degenerative diseases
- Ataxin-7 oligonucleotide knock-down to treat sca7 retinal and cerebellar disease (website)
- Choroidal blood flow imaging with spectral domain oct (website)
- COLOR VISION IN INHERITED RETINAL DEGENERATIONS (website)
- Developing efficient aav vectors for photoreceptor targeting via the vitreous (website)
- Development of redox-active therapies for ischemic optic neuropathy
- Dhdds and retinal degeneration (website)
- Directed evolution of adeno-associated virus for retinal gene therapy (website)
- Evaluating a non-contact fundus camera for retinopathy of prematurity screening (website)
- Fiber cell membrane organization-role in lens architecture and function
- Fully automatic rop screening system: neoscan (website)
- GENERATION OF INDUCED PLURIPOTENT STEM (IPS) CELL LINES FROM SOMATIC CELLS OF PARTICIPANTS WITH EYE DISEASES AND FROM SOMATIC CELLS OF MATCHED CONTROLS (website)
- Immune mechanisms in ocular graft versus host disease (website)
- Modeling photoreceptor development and disease using human pluripotent stem cells (website)
- Nanoparticle-mediated gene delivery for rhodopsin-associated retinitis pigmentosa (website)
- Non-linear optical collagen cross-linking (nlo cxl) for treatment of keratoconus (website)
- Phage display selection of antiangiogenic cmg2 cyclic peptide antagonists
- Physiologically based markers of idiopathic intracranial hypertension (website)
- PILOT STUDY TO EVALUATE ORAL MINOCYCLINE IN THE TREATMENT OF CYSTOID MACULAR EDEMA ASSOCIATED WITH RETINITIS PIGMENTOSA (website)
- Preclinical preparation for the boston retinal implant device
- Prevention of retinal degeneration by transgenic autologous stem cells (website)
- Programmed cell death in anterior eye development and peters’ anomaly (website)
- Quantitative fundus autofluorescence in retinal disorders (website)
- Rhodopsin-mediated phospholipid flipping (website)
- Role of optical aberrations in 3d space perception: implications for keratoconus (website)
- Suppressing thyroid hormone signaling to protect cones in retinal degeneration (website)
- Transcriptional regulation of retinal mitochondrial function and cell cycle
2013
- 3D Image Analysis Approach to Determine Severity and Cause of Optic Nerve Edema (website)
- A Drosophila Model for Charcot-Marie-Tooth 2B Disease (website)
- Automated retinopathy of prematurity classification using machine learning (website)
- Circulating Immune Biomarkers and Retinopathy of Prematurity (website)
- Coherent light scattering for early detection of retinal disease (website)
- Compacted DNA Nanoparticles for Ocular Therapy (website)
- Cyclodextrins as potential treatment for age related macular degeneration (website)
- Delaying Cone Death in Retinitis Pigmentosa (website)
- Documentation of Novel Keratoconus Markers: In Vitro and In Vivo
- EYA in Retinal Angiogenesis (website)
- Gene Discovery in Familial Keratoconus (website)
- Gene therapy to support cone metabolism in retinitis pigmentosa (website)
- Investigation of nuclear transport dysfunction in an ocular model of FTLD (website)
- LARGE ANIMAL THERAPY STUDIES (website)
- Modulating Ocular/Retinal Blood Flow and Visual Function in Retinitis Pigmentosa
- PRE-CLINICAL AND CLINICAL STUDIES OF NTBC AS A POTENTIAL TREATMENT FOR ALBINISM (website)
- Processing Streams In Mouse Visual Cortex (website)
- RETIVUE WF – A handheld, high-resolution, wide-field retinal imager
- Role of impaired protein degradation in photoreceptor degeneration (website)
- Role of Optineurin in Ocular Herpes Infection (website)
- The role of plasmacytoid dendritic cells in corneal immunity (website)
- Unfolded Protein Response as a Therapeutic Target for ADRP Animal Models (website)
2012
- Adaptive optics scanning laser ophthalmoscope-based microperimetry: establishing website)
- Bcl-2 and ocular neovascularization (website)
- CLINICAL RESEARCH AND PROTOCOL SUPPORT SERVICES (website)
- Cone opsins in photoreceptor degeneration (website)
- Cortical Areas and Neural Connections Underlying Scene Processing (website)
- Defining the neural correlates of ensemble representation (website)
- Function of ciliary disease protein Retinitis Pigmentosa GTPase Regulator (RPGR) (website)
- HDAC4-mediated Photoreceptor Protection in Retinal Degeneration (website)
- HUMAN RHODOPSIN-ADRP STUDIES (website)
- LARGE ANIMAL (DOG) EXPERIMENTAL SUPPORT MODULE (website)
- Large animal therapy studies (website)
- LCA Gene Therapy in Somatic Cell-Derived Induced Pluripotent Stem Cells (website)
- Molecular Basis of Human Visual System Disorders (website)
- Molecular Pathophysiology of Retinal Degeneration in Bardet-Biedl Syndrome (website)
- NATURAL HISTORY AND GENETIC STUDIES OF USHER SYNDROME (website)
- NATURAL HISTORY OF OCULAR GVHD (website)
- Neuroprotective agents for retinal diseases (website)
- OPHTHALMIC DNA DIAGNOSTIC TESTING SERVICE (website)
- Optimization of an Optogenetic-Based Vision Therapy for Retinitis Pigmentosa (website)
- Pathogenesis of Vaccinia virus keratitis (website)
- Postnatal Growth and Retinopathy of Prematurity (G-ROP) Studies (website)
- Regulation of Ocular Neural Crest and its Implications in Congenital Eye Diseases (website)
- Regulation of the Hippo pathway and its role in uveal melanoma (website)
- RETINAL AGING AND INHERITED NEURODEGENERATIVE DISEASES (website)
- Role of Nrf2 in retinal vascularization and ROP (website)
- Sigma-1 Chaperone-Mediated in vivo Neuroprotection in the Retina (website)
- Structure & Function of Ganglion-Cell Photoreceptors Contributing to Form Vision (website)
- The Role of Nephrocystin-5 in Retinal Degeneration (website)
- Visual outcome measures in children with optic pathway gliomas (website)
2011
- Carotinoids in Vision (website)
- Completing genetic analysis of the ABCA4 locus (website)
- Cortical Structure and Function in Blindness and following Restored Vision (website)
- DIAGNOSIS AND TREATMENT OF OCULAR INFLAMMATORY DISEASE (UVEITIS) (website)
- DISEASE MECHANISM AND THERAPIES FOR RETINAL DEGENERATION (website)
- Evaluation of stem cell-derived retinal pigment epithelial cells for retinal disease
- Formation and New Components of the Usher 2 Protein Complex in Photoreceptors (website)
- Gene Expression in Nonspecific Orbital Inflammatory Disease ( website)
- GENOMIC ANALYSIS IN GENES RESPONSIBLE FOR EYE ABNORMALITIES IN PATIENTS (website)
- IMMUNOGENETIC MECHANISMS IN BECHET’S DISEASE (website)
- INHERITED OCULAR DISEASES (website)
- INTERVENTIONAL APPROACHES FOR RESTORING VISION (website)
- Investigating the Role of Hypoxia Inducible Factors in Pathological Retinal Angio (website)
- Longitudinal Neuroimaging of Leber’s Congenital Amaurosis After Gene Therapy (website)
- MECHANISMS OF RETINAL DEGENERATION IN INHERITED DISEASES (website)
- Modifiers of Retinal Phenotypes in Ciliopathies (website)
- MOLECULAR AND IMMUNOPATHOLOGY OF EXPERIMENTAL AND CLINICAL OCULAR DISEASES (website)
- Molecular Mechanisms of Human Retinal Disease (website)
- Mouse model for eyelid disease: Congenital blepharophimosis (website)
- MULTICENTER UVEITIS TRIAL USING A STEROID IMPLANT AND INFLAMMATORY MEDIATORS (website)
- NATIONAL OPHTHALMIC DISEASE GENOTYPING AND PHENOTYPING NETWORK – EYEGENE (website)
- NEI GENETIC ENGINEERING CORE (website)
- Neuronal Cell Cycle and Survival (website)
- NEURO-OPHTHALMIC MECHANISMS OF DISEASE (website)
- New Approach to promote optic nerve regeneration and vision restoration (website)
- Outcomes of children with juvenile idiopathic arthritis-associated uveitis (website)
- Pax6, CtBP and the regulation of transcription in Drosophilia eye specification (website)
- PRE-CLINICAL STUDIES OF NTBC AS A POTENTIAL TREATMENT FOR ALBINISM (website)
- Prevention of Retinopathy of Prematurity with a Novel Bifunctional Redox Reagent (website)
- PRIMARY INTRAOCULAR LYMPHOMA AND ANIMAL MODELS (website)
- Regulation of normal and Leber congenital amaurosis-associated RPE65s (website)
- RETINAL GENE THERAPY (website)
- Serotonin Receptor Modulation of Neurotrophic Factors in the Retina (website)
- Statisitical design, monitoring & coord. Of vision clinical trials & epidemiology (website)
- The Pathogenesis of RNA Splicing Factor RP (website)
- The role of microRNAs in the development and differentiation of mouse photorecept (website)
- The Role of the Nicotinic Cholinergic Pathway in Retinopathy of Prematurity (website)
- Therapeutic approaches for ABCA4-associated disorders (website)
- Therapeutic Corneal Cross-linking Using Aliphatic Beta-Nitroalcohols (website)
- Understanding uveitis in a multi-system disease model of spondyloarthropathy (website)
- Zebrafish Model of Human Corneal Development and Disease (website)
- Zonule Assembly and Ectopia Lentis (website)
2010
- A New LCA Model By Polarity Gene Ablation (website)
- Clinical and Genetic Analysis of Retinopathy of Prematurity (website)
- Development of a non-rodent model using light-activated channel technology to cur (website)
- Endogenous Specific Inhibitor of Corneal Lymphangiogenesis (website)
- Endoplasmic Reticulum Stress in Retinal Degeneration (website)
- Illuminating the process of rod outer segment morphogenesis (website)
- In-vivo, High Contrast Imaging of the Human Rod Photoreceptor Mosaic (website)
- P23H Rhodopsin Mutant Swine Model of Reninitis Pigmentosa (website)
- Pharmacological Treatment of Retinal Diseases (website)
- Quality control mechanisms against misfolded rhodopsins in Drosophila (website)
- Rod Cone Interactions in Mesopic Vision (website)
- Role of corneal neuropeptides in the pathogenesis of herpetic stromal keratitis (website)
- Telemedicine Approaches to Evaluating Acute-phase ROP – eROP (website)
- The Role of RNA Splicing Factors in Retinal Degeneration (website)
- Therapeutic Ocular HSV Vaccine in HLA Transgenic Rabbits (website)