May 20, 2015
deCODE Genetics, a US based company, known for analysing the human genome, has recently published four papers in Nature Genetics, built on genomic data from Iceland from over 100,000 individuals. One of the papers reports on the frequency and utility of human gene knockouts, wherein they identified 1,171 knocked-out genes. Additionally, the investigators demonstrated that 7.7% of the 104,000 studied individuals have at least one gene knocked. The authors believe that the “examination of health and other traits in these individuals should provide a unique way to study directly the effect of specific genes on human biology and potentially contribute to the development of new drugs and diagnostics“.